Publications
Selected publications from the Li Lab and collaborators. Citations are organized by year and linked to the publisher, DOI, preprint, or scholarly record.
2026
Kriukova K, Li L, Staba RJ, Boswell M, Asifriyaz T, Thomas R, Gugger JJ, Shamas M, Diaz‐Arrastia R, Buitrago Blanco M, Engel J, Vespa PM, Duncan D. High-frequency oscillations after acute hemorrhagic traumatic brain injury: insights into posttraumatic epilepsy development.Epilepsia. 2026. doi:10.1002/epi.70235. Article link
Jafari N, Yeh HJ, Kumar U, Harris NG, Stern JM, Engel J, Bragin A, Li L. Etiology-specific trajectories of longitudinal functional connectivity and network topology in posttraumatic and mesial temporal lobe epileptogenesis.Experimental Neurology. 2026; article 115861. doi:10.1016/j.expneurol.2026.115861. Article link
Zolfaghar M, Wang M, Li L, Lee MY. Differential neurodevelopmental disruption by Bisphenol A (BPA) and Valproic Acid (VPA) in human forebrain organoids.bioRxiv. 2026. doi:10.64898/2026.03.15.711882. Article link
2025
Tao X, Kumar U, Wang M, Manglani K, Zhu C, Jones MR, Bombino A, Bragin A, Cole G, Vossel K, Engel J, Frautschy SA, Li L. Disruption of electrophysiological rhythms and memory impairment in an Alzheimer's transgenic rat model.Alzheimer's Research & Therapy. 2025;17(1):200. doi:10.1186/s13195-025-01841-4. Article link
Nguyen N, Wang M, Li L, Chan CT. A genetic safeguard for eliminating target genes in synthetic probiotics in a gut environment.iScience. 2025;28(8). doi:10.1016/j.isci.2025.113027. Article link
Kriukova K, Staba R, Li L, Duncan D. High-frequency oscillations (HFOs) in the acute period of moderate to severe traumatic brain injury (TBI).Journal of Neurotrauma. 2025;42(13-14). Article link
Jafari N, He L, Khalil CB, Yeh HJ, Harris NG, Stern JM, Engel J Jr., Bragin A, Li L. Intrinsic brain network stability during kainic acid-induced epileptogenesis.Epilepsia Open. 2025;10(2):508-520. doi:10.1002/epi4.70002. Article link
Kang S, Li L, Shahdadian S, Wu A, Liu H. Site- and electroencephalogram-frequency-specific effects of 800-nm prefrontal transcranial photobiomodulation on electroencephalogram global network topology in young adults.Neurophotonics. 2025;12(1):015011. doi:10.1117/1.NPh.12.1.015011. Article link
You J, Fuchs J, Wang M, Hu Q, Tao X, Krolczyk E, Tirumala T, Bragin A, Liu H, Engel J Jr, Li L. Preventive effects of transcranial photobiomodulation on epileptogenesis in a kainic acid-induced rat epilepsy model.Experimental Neurology. 2025;383:115005. doi:10.1016/j.expneurol.2024.115005. Article link
2024
Wang M, Dinarvand D, Chan CTY, Bragin A, Li L. Photobiomodulation as a potential treatment for Alzheimer's disease: a review paper.Brain Sciences. 2024;14(11):1064. doi:10.3390/brainsci14111064. Article link
Kinshuk S, Li L, Meckes B, Chan CTY. Sequence-based protein design: a review of using statistical models to characterize coevolutionary traits for developing hybrid proteins as genetic sensors.International Journal of Molecular Sciences. 2024;25(15):8320. doi:10.3390/ijms25158320. Article link
2023
Zhu F, Wang H, Li L, Bragin A, Cao D, Cheng Y. Intracranial electrophysiological recordings on a swine model of mesial temporal lobe epilepsy.Frontiers in Neurology. 2023;14:1077702. doi:10.3389/fneur.2023.1077702. Article link
2022
Zhou Y, You J, Kumar U, Weiss SA, Bragin A, Engel J Jr, Papadelis C, Li L. An approach for reliably identifying high-frequency oscillations and reducing false-positive detections.Epilepsia Open. 2022;7(4):674-686. doi:10.1002/epi4.12647. Article link
Liu AA, Henin S, Abbaspoor S, Bragin A, Buffalo EA, Farrell JS, Foster DJ, Frank LM, Gedankien T, Gotman J, Guidera JA, Hoffman KL, Jacobs J, Kahana MJ, Li L, Liao Z, Lin JJ, Losonczy A, Malach R, van der Meer MA, McClain K, McNaughton BL, Norman Y, Navas-Olive A, de la Prida LM, Rueckemann JW, Sakon JJ, Skelin I, Soltesz I, Staresina BP, Weiss SA, Wilson MA, Zaghloul KA, Zugaro M, Buzsáki G. A consensus statement on detection of hippocampal sharp wave ripples and differentiation from other fast oscillations.Nature Communications. 2022;13(1):6000. doi:10.1038/s41467-022-33536-x. Article link
You J, Huang H, Chan CTY, Li L. Pathological targets for treating temporal lobe epilepsy: discoveries from microscale to macroscale.Frontiers in Neurology. 2022; article 2381. doi:10.3389/fneur.2021.779558. Article link
2021
Li L, Kumar U, You J, Zhou Y, Weiss SA, Engel J, Bragin A. Spatial and temporal profile of high-frequency oscillations in posttraumatic epileptogenesis.Neurobiology of Disease. 2021;161:105544. doi:10.1016/j.nbd.2021.105544. Article link
Zhou Y, You J, Zhu F, Bragin A, Engel J, Li L. Automatic electrophysiological noise reduction and epileptic seizure detection for stereoelectroencephalography.Proceedings of the 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). 2021. doi:10.1109/EMBC46164.2021.9630651. Article link
Kumar U, Li L, Bragin A, Engel J Jr. Spike and wave discharges and fast ripples during posttraumatic epileptogenesis.Epilepsia. 2021;62(8):1842-1851. doi:10.1111/epi.16958. Article link
Li L, He L, Harris N, Zhou Y, Engel J Jr, Bragin A. Topographical reorganization of brain functional connectivity during an early period of epileptogenesis.Epilepsia. 2021;62(5):1231-1243. doi:10.1111/epi.16863. Article link
2020
You J, Bragin A, Liu H, Li L. Preclinical studies of transcranial photobiomodulation in the neurological diseases.Translational Biophotonics. 2020. doi:10.1002/tbio.202000024. Article link
Choi D, Li L, Liu H, Zeng L. A recursive partitioning approach for subgroup identification in brain-behaviour correlation analysis.Pattern Analysis and Applications. 2020;23(1):161-177. doi:10.1007/s10044-018-00775-y. Article link
2019
Bragin A, Li L, Masmanidis SC, Engel J Jr. DOWN state in the anterior cingulate and prelimbic areas in rats during immobility.bioRxiv. 2019. doi:10.1101/847913. Article link
Cao D, Chen Y, Liao J, Nariai H, Li L, Zhu Y, Zhao X, Hu Y, Wen F, Zhai Q. Scalp EEG high frequency oscillations as a biomarker of treatment response in epileptic encephalopathy with continuous spike-and-wave during sleep (CSWS).Seizure. 2019;71:151-157. doi:10.1016/j.seizure.2019.05.023. Article link
Li L, Bragin A, Staba R, Engel J Jr. Unit firing and oscillations at seizure onset in epileptic rodents.Neurobiology of Disease. 2019;127:382-389. doi:10.1016/j.nbd.2019.03.027. Article link
2018
Li L, Babawale O, Yennu A, Trowbridge C, Hulla R, Gatchel RJ, Liu H. Whole-cortical graphical networks at wakeful rest in young and older adults revealed by functional near-infrared spectroscopy.Neurophotonics. 2018;5(3):035004. doi:10.1117/1.NPh.5.3.035004. Article link
Kriukova KK, Bragin A, Alexandrova E, Li L. Association between occurrence of hippocampal spindles and hippocampal interictal spiking.Neurology. 2018;90(15 Suppl):P2.280. doi:10.1212/WNL.90.15_supplement.P2.280. Article link
Culaclii S, Kim B, Lo YK, Li L, Liu W. Online artifact cancelation in same-electrode neural stimulation and recording using a combined hardware and software architecture.IEEE Transactions on Biomedical Circuits and Systems. 2018;12(3):601-613. doi:10.1109/TBCAS.2018.2816464. Article link
Li L, Patel M, Almajano J, Engel J Jr, Bragin A. Extrahippocampal high-frequency oscillations during epileptogenesis.Epilepsia. 2018;59(4):e51-e55. doi:10.1111/epi.14041. Article link
Li L, Kriukova K, Engel J Jr., Bragin A. Seizure development in the acute intrahippocampal epileptic focus.Scientific Reports. 2018;8(1):1423. doi:10.1038/s41598-018-19675-6. Article link
2017
Li L, Cazzell M, Zeng L, Liu H. Are there gender differences in young vs. aging brains under risk decision-making? An optical brain imaging study.Brain Imaging and Behavior. 2017;11(4):1085-1098. doi:10.1007/s11682-016-9580-z. Article link
2016
Li L, Cazzell M, Babawale O, Liu H. Automated voxel classification used with atlas-guided diffuse optical tomography for assessment of functional brain networks in young and older adults.Neurophotonics. 2016;3(4):045002. doi:10.1117/1.NPh.3.4.045002. Article link
Bragin A, Li L, Almajano J, Alvarado‐Rojas C, Reid AY, Staba RJ, Engel J Jr. Pathologic electrographic changes after experimental traumatic brain injury.Epilepsia. 2016;57(5):735-745. doi:10.1111/epi.13359. Article link
Li L, Babawale O, Cazzell M, Liu H. Assessment of resting-state brain networks in young and older adults by automatic voxel classification with atlas-guided diffuse optical tomography.Optics and the Brain. 2016;JW3A.46. doi:10.1364/CANCER.2016.JW3A.46. Article link
2015
Li L, Zeng L, Lin ZJ, Cazzell M, Liu H. Tutorial on use of intraclass correlation coefficients for assessing intertest reliability and its application in functional near-infrared spectroscopy-based brain imaging.Journal of Biomedical Optics. 2015;20(5):050801. doi:10.1117/1.JBO.20.5.050801. Article link
2014
Lin Z, Li L, Cazzell M, Liu H. Atlas-guided volumetric diffuse optical tomography enhanced by generalized linear model analysis to image risk decision-making responses in young adults.Human Brain Mapping. 2014;35(8):4249-4266. doi:10.1002/hbm.22459. Article link
Li L, Zeng L, Cazzell M, Liu H. A statistical approach to assess measurement reliability of functional DOT for brain imaging.Biomedical Optics. 2014;BM3A.27. doi:10.1364/BIOMED.2014.BM3A.27. Article link
Li L, Cazzell M, Liu H. Investigation of age difference under risk decision-making using atlas-guided diffuse optical tomography.Biomedical Optics. 2014;BM3A.26. doi:10.1364/BIOMED.2014.BM3A.26. Article link
Lin ZJ, Ren M, Li L, Liu Y, Su J, Yang SH, Liu H. Interleaved imaging of cerebral hemodynamics and blood flow index to monitor ischemic stroke and treatment in rat by volumetric diffuse optical tomography.NeuroImage. 2014;85:566-582. doi:10.1016/j.neuroimage.2013.07.020. Article link
2013
Li L, Lin Z, Cazzell M, Liu H. Test-retest assessment of functional near-infrared spectroscopy to measure risk decision making in young adults.Photonic Therapeutics and Diagnostics IX. 2013;8565:578-584. doi:10.1117/12.2005552. Article link
Lin ZJ, Li L, Cazzell M, Liu H. Monitoring of human brain functions in risk decision-making task by diffuse optical tomography using voxel-wise general linear model.Photonic Therapeutics and Diagnostics IX. 2013;8565:568-577. doi:10.1117/12.2005538. Article link
2012
Cazzell M, Li L, Lin ZJ, Patel SJ, Liu H. Comparison of neural correlates of risk decision making between genders: an exploratory fNIRS study of the Balloon Analogue Risk Task (BART).NeuroImage. 2012;62(3):1896-1911. doi:10.1016/j.neuroimage.2012.05.030. Article link
Lin ZJ, Ren M, Li L, Yang S, Liu H. Diffuse optical tomography to study ischemic stroke in preclinical rat models.Biomedical Optics. 2012;BTu3A.32. doi:10.1364/BIOMED.2012.BTu3A.32. Article link
Li L, Lin ZJ, Cazzell M, Liu H. Measurement of brain activations to examine gender-specific risk decision making using functional near infrared spectroscopy (fNIRS).Biomedical Optics. 2012;BTu3A.34. doi:10.1364/BIOMED.2012.BTu3A.34. Article link
Lin ZJ, Niu H, Li L, Liu H. Volumetric diffuse optical tomography for small animals using a CCD-camera-based imaging system.International Journal of Optics. 2012;2012(1):276367. doi:10.1155/2012/276367. Article link
2011
Niu H, Li L, Bhave GS, Lin ZJ, Tian F, Khosrow B, Zhang R, Liu H. Investigation of cerebral hemodynamic changes during repeated sit-stand maneuver using functional near-infrared spectroscopy.Dynamics and Fluctuations in Biomedical Photonics VIII. 2011;7898:121-128. doi:10.1117/12.875944. Article link